Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5

Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5

Pseudolaric Acid B (PAB), diterpenoid isolated from the root bark of <i>Pseudolarix kaempferi</i> Gordon tree (Pinaceae), exhibits an anti-proliferative and apoptotic activity in various cancer cell lines but to date, the effects of PAB on head and neck cancer (HNC) cell lines remain to...

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Bibliographic Details
Main Authors: Su-Jung Choi, Chi-Hyun Ahn, In-Hyoung Yang, Bohwan Jin, Won Woo Lee, Ji-Hoon Kim, Min-Hye Ahn, Neeti Swarup, Kyoung-Ok Hong, Ji-Ae Shin, Nam-Tae Woo, Seong Doo Hong, Jae-Il Lee, Sung-Dae Cho
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
pseudolaric acid b
oral cancer
death receptor 5
caspase-8 apoptosis
Online Access:https://www.mdpi.com/1420-3049/24/20/3715

Internet

https://www.mdpi.com/1420-3049/24/20/3715

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