Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions

Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions

Neurodegenerative diseases (NDDs) such as Alzheimer’s disease, Parkinson’s disease and Huntington’s disease (HD), amyotrophic lateral sclerosis, and prion diseases are all characterized by the accumulation of protein aggregates (amyloids) into inclusions and/or plaques. The ubiquitous presence of am...

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Bibliographic Details
Main Authors: Botond Penke, Ferenc Bogár, Tim Crul, Miklós Sántha, Melinda E. Tóth, László Vígh
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
neurodegenerative diseases
neuroprotection
endoplasmic reticulum associated degradation
ubiquitin-proteasome system
autophagy
heat shock proteins
Hsp-inducers
autophagy modulating drugs
Online Access:http://www.mdpi.com/1422-0067/19/1/325

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http://www.mdpi.com/1422-0067/19/1/325

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