Protection against Glucolipotoxicity by High Density Lipoprotein in Human PANC-1 Hybrid 1.1B4 Pancreatic Beta Cells: The Role of microRNA

Protection against Glucolipotoxicity by High Density Lipoprotein in Human PANC-1 Hybrid 1.1B4 Pancreatic Beta Cells: The Role of microRNA

High-density lipoproteins provide protection against the damaging effects of glucolipotoxicity in beta cells, a factor which sustains insulin secretion and staves off onset of type 2 diabetes mellitus. This study examines epigenetic changes in small non-coding microRNA sequences induced by high dens...

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Bibliographic Details
Main Authors: Jamie M.R. Tarlton, Richard J. Lightbody, Steven Patterson, Annette Graham
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biology
Subjects:
glucolipotoxicity
beta-cells
high density lipoprotein
microRNA
hsa-miR-21-5p
Online Access:https://www.mdpi.com/2079-7737/10/3/218

Internet

https://www.mdpi.com/2079-7737/10/3/218

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