Computer-aided identification of a series of novel ligands showing high potency as hepatitis C virus NS3/4A protease inhibitors

Computer-aided identification of a series of novel ligands showing high potency as hepatitis C virus NS3/4A protease inhibitors

Abstract Background Hepatitis C virus (HCV) is a global medical condition that causes several life-threatening chronic diseases in the liver. The conventional interferon-free treatment regimens are currently in use by a blend of direct-acting antiviral agents (DAAs) aiming at the viral NS3 protease....

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Bibliographic Details
Main Authors: Stephen Ejeh, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen E. Abechi
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:Bulletin of the National Research Centre
Subjects:
Computer-aided drug design
QSAR
HCV NS3/4A protease inhibitors
Molecular docking
Molecular descriptors
Online Access:https://doi.org/10.1186/s42269-020-00467-w

Internet

https://doi.org/10.1186/s42269-020-00467-w

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