Computer-aided identification of a series of novel ligands showing high potency as hepatitis C virus NS3/4A protease inhibitors
Abstract Background Hepatitis C virus (HCV) is a global medical condition that causes several life-threatening chronic diseases in the liver. The conventional interferon-free treatment regimens are currently in use by a blend of direct-acting antiviral agents (DAAs) aiming at the viral NS3 protease....
Main Authors: | Stephen Ejeh, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen E. Abechi |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2021-01-01
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Series: | Bulletin of the National Research Centre |
Subjects: | |
Online Access: | https://doi.org/10.1186/s42269-020-00467-w |
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