Organic mononitrites of 1,2-propanediol act as an effective NO-releasing vasodilator in pulmonary hypertension and exhibit no cross-tolerance with nitroglycerin in anesthetized pigs

Organic mononitrites of 1,2-propanediol act as an effective NO-releasing vasodilator in pulmonary hypertension and exhibit no cross-tolerance with nitroglycerin in anesthetized pigs

Kristofer F Nilsson,1,2 Waldemar Goździk,3 Claes Frostell,4 Stanisław Zieliński,3 Marzena Zielińska,3 Kornel Ratajczak,5 Piotr Skrzypczak,5 Sylwia Rodziewicz,5 Johanna Albert,6 Lars E Gustafsson1,† 1Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden; 2Dep...

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Bibliographic Details
Main Authors: Nilsson KF, Goździk W, Frostell C, Zieliński S, Zielińska M, Ratajczak K, Skrzypczak P, Rodziewicz S, Albert J, Gustafsson LE
Format: Article
Language:English
Published: Dove Medical Press 2018-03-01
Series:Drug Design, Development and Therapy
Subjects:
nitrites
nitrates
nitric oxide donors
tachyphylaxis
Online Access:https://www.dovepress.com/organic-mononitrites-of-12-propanediol-act-as-an-effective-no-releasin-peer-reviewed-article-DDDT

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https://www.dovepress.com/organic-mononitrites-of-12-propanediol-act-as-an-effective-no-releasin-peer-reviewed-article-DDDT

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