Resistance is futile: overcoming resistance to targeted therapies in lung adenocarcinoma

Abstract The advent of genomics has led to the identification of specific “driver” mutations in oncogenic kinases, and the development of targeted small molecule inhibitors to block their tumor-driving functions. These specific inhibitors have been a clinical success, and often significantly prolong...

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Bibliographic Details
Main Authors: Dana S. Neel, Trever G. Bivona
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-017-0007-0