Abundance of Non-Polarized Lung Macrophages with Poor Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)

Lung macrophages are the key immune effector cells in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Several studies have shown an increase in their numbers in bronchoalveolar lavage fluid (BAL) of subjects with COPD compared to controls, suggesting a pathogenic role in disease in...

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Bibliographic Details
Main Authors: Kentaro Akata, Kei Yamasaki, Fernando Sergio Leitao Filho, Chen Xi Yang, Hiroto Takiguchi, Basak Sahin, Beth A Whalen, Cheng Wei Tony Yang, Janice M Leung, Don D Sin, Stephanus van Eeden
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/10/398