SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness

SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness

Papillary thyroid carcinoma (PTC) is the most common thyroid cancer with a rapidly increasing incidence globally. Bioinformatics analyses suggested that SHCBP1 (SHC SH2 Domain-Binding Protein 1) was significantly up-regulated in PTC tumor tissues, which was further confirmed by immunohistochemical s...

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Bibliographic Details
Main Authors: Houfa Geng, Mengzhe Guo, Wei Xu, Xiu Zang, Tingting Wu, Fei Teng, Yu Wang, Xuekui Liu, Xiuli Wang, Qiang Sun, Jun Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Endocrinology
Subjects:
PTC
SHCBP1
cell stemness
EMT
integrin
collagen
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.613879/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.613879/full

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