Genetic Association Reveals Protection against Recurrence of Clostridium difficile Infection with Bezlotoxumab Treatment

Genetic Association Reveals Protection against Recurrence of Clostridium difficile Infection with Bezlotoxumab Treatment

Clostridium difficile infection is associated with significant clinical morbidity and mortality; antibacterial treatments are effective, but recurrence of C. difficile infection is common. In this genome-wide association study, we explored whether host genetic variability affected treatment response...

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Bibliographic Details
Main Authors: Judong Shen, Devan V. Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, Xun Xu, David Nickle, Emily R. Holzinger, Aparna Chhibber, Mark H. Wilcox, Rebecca L. Blanchard, Peter M. Shaw
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mSphere
Subjects:
clostridium difficile
antibacterials
bezlotoxumab
genomics
Online Access:https://doi.org/10.1128/mSphere.00232-20

Internet

https://doi.org/10.1128/mSphere.00232-20

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