Size and Shape Filtering of Malignant Cell Clusters within Breast Tumors Identifies Scattered Individual Epithelial Cells as the Most Valuable Histomorphological Clue in the Prognosis of Distant Metastasis Risk

Size and Shape Filtering of Malignant Cell Clusters within Breast Tumors Identifies Scattered Individual Epithelial Cells as the Most Valuable Histomorphological Clue in the Prognosis of Distant Metastasis Risk

Survival and life quality of breast cancer patients could be improved by more aggressive chemotherapy for those at high metastasis risk and less intense treatments for low-risk patients. Such personalized treatment cannot be currently achieved due to the insufficient reliability of metastasis risk p...

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Bibliographic Details
Main Authors: Velicko Vranes, Nemanja Rajković, Xingyu Li, Konstantinos N. Plataniotis, Nataša Todorović Raković, Jelena Milovanović, Ksenija Kanjer, Marko Radulovic, Nebojša T. Milošević
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
breast cancer
tumor budding
invasion
tumor cell dissociation
individual cell
prognosis
metastasis
image analysis
particle analysis
pan-cytokeratin
histopathology
Online Access:https://www.mdpi.com/2072-6694/11/10/1615

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https://www.mdpi.com/2072-6694/11/10/1615

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