Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation

Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation

The 6-epimer of the plakortide H acid (1), along with the endoperoxides plakortide E (2), plakortin (3), and dihydroplakortin (4) have been isolated from a sample of the Caribbean sponge Plakortis halichondrioides. To perform a comparative study on the cytotoxicity towards the drug-sensitive leukemi...

Full description

Bibliographic Details
Main Authors: Tanja Schirmeister, Swarna Oli, Hongmei Wu, Gerardo Della Sala, Valeria Costantino, Ean-Jeong Seo, Thomas Efferth
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Marine Drugs
Subjects:
Caribbean sponge
plakortide
endoperoxide
leukemia
multi-drug resistant leukemia
cytotoxicity
Online Access:http://www.mdpi.com/1660-3397/15/3/63

Internet

http://www.mdpi.com/1660-3397/15/3/63

Similar Items