Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration

Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration

The immune response of the CNS is a defense mechanism activated upon injury to initiate repair mechanisms while chronic over-activation of the CNS immune system (termed neuroinflammation) may exacerbate injury. The latter is implicated in a variety of neurological and neurodegenerative disorders suc...

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Bibliographic Details
Main Authors: Maria Emilia Figueiredo-Pereira, Patricia eRockwell, Thomas eSchmidt-Glenewinkel, Peter eSerrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Mitochondria
neurodegeneration
Neuroinflammation
Upp
J2 prostaglandins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00104/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00104/full

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