Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

The oxidative stress and cellular apoptosis by environmental factor including cigarette smoke induces alveolar airway remodeling leading to chronic obstructive pulmonary disease (COPD). Recently, the receptor for advanced glycan end products (RAGE) which is highly expressed in alveolar epithelium is...

Full description

Bibliographic Details
Main Authors: Hanbyeol Lee, Jooyeon Lee, Seok-Ho Hong, Irfan Rahman, Se-Ran Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
cigarette smoke extract
COPD
FPS-ZM1
RAGE
DAMP
Nrf2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00684/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00684/full

Similar Items