High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.

VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies (Ab) to placental parasites at delivery have been associated with improved pregnancy outcomes, but Ab levels and how early in p...

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Bibliographic Details
Main Authors: Yeung Lo Tutterrow, Ali Salanti, Marion Avril, Joseph D Smith, Ian S Pagano, Simon Ako, Josephine Fogako, Rose G F Leke, Diane Wallace Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3383675?pdf=render