Intrinsic denervation of the colon is associated with a decrease of some colonic preneoplastic markers in rats treated with a chemical carcinogen

Intrinsic denervation of the colon is associated with a decrease of some colonic preneoplastic markers in rats treated with a chemical carcinogen

Denervation of the colon is protective against the colon cancer; however, the mechanisms involved are unknown. We tested the hypothesis that the denervated colonic mucosa could be less responsive to the action of the chemical carcinogen dimethylhydrazine (DMH). Three groups of 32 male Wistar rats we...

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Bibliographic Details
Main Authors: M.V.O. Vespúcio, A. Turatti, P. Modiano, E.C. de Oliveira, S.R.M. Chicote, A.M.P. Pinto, S.B. Garcia
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2008-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Colon cancer
Dimethylhydrazine
Benzalkonium chloride
Aberrant crypt foci
ß-catenin
Megacolon
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000400009

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000400009

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