IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes

IRF-1: a key regulator in rheumatoid Arthritis Thomas Karonitsch at the Medical University of Vienna, Austria, and colleagues showed that activation of the protein interferon regulatory factor 1 (IRF-1) in human synoviocytes promoted the expression of genes that contribute to sustained synovial infl...

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Bibliographic Details
Main Authors: Michael Bonelli, Karolina Dalwigk, Alexander Platzer, Isabel Olmos Calvo, Silvia Hayer, Birgit Niederreiter, Johannes Holinka, Florian Sevelda, Thomas Pap, Günter Steiner, Giulio Superti-Furga, Josef S. Smolen, Hans P. Kiener, Thomas Karonitsch
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0267-6

Internet

https://doi.org/10.1038/s12276-019-0267-6

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