In vivo Functional Genomics for Undiagnosed Patients: The Impact of Small GTPases Signaling Dysregulation at Pan-Embryo Developmental Scale

In vivo Functional Genomics for Undiagnosed Patients: The Impact of Small GTPases Signaling Dysregulation at Pan-Embryo Developmental Scale

While individually rare, disorders affecting development collectively represent a substantial clinical, psychological, and socioeconomic burden to patients, families, and society. Insights into the molecular mechanisms underlying these disorders are required to speed up diagnosis, improve counseling...

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Bibliographic Details
Main Authors: Antonella Lauri, Giulia Fasano, Martina Venditti, Bruno Dallapiccola, Marco Tartaglia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
small GTPases
rare diseases
undiagnosed patients
next generation sequencing
in vivo models
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.642235/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.642235/full

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