Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex

Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex

Summary: Influenza A virus (IAV) infection stimulates a type I interferon (IFN-I) response in host cells that exerts antiviral effects by inducing the expression of hundreds of IFN-stimulated genes (ISGs). However, most ISGs are poorly studied for their roles in the infection of IAV. Herein, we demo...

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Bibliographic Details
Main Authors: Nina Sun, Chunfeng Li, Xiao-Feng Li, Yong-Qiang Deng, Tao Jiang, Na-Na Zhang, Shulong Zu, Rong-Rong Zhang, Lili Li, Xiang Chen, Ping Liu, Sarah Gold, Ning Lu, Peishuang Du, Jingfeng Wang, Cheng-Feng Qin, Genhong Cheng
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Cell Reports
Subjects:
type I interferon
IFN-stimulated genes
SERTAD3
IAV
RNA-dependent RNA polymerase
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720313310

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http://www.sciencedirect.com/science/article/pii/S2211124720313310

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