A New Computational Approach to Evaluating Systemic Gene–Gene Interactions in a Pathway Affected by Drug LY294002
In this study, we investigate how drugs systemically affect genes via pathways by integrating information from interactions between chemical compounds and molecular expression datasets, and from pathway information such as gene sets using mathematical models. First, we adopt drug-induced gene expres...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Processes |
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| Online Access: | https://www.mdpi.com/2227-9717/8/10/1230 |