Robust Linear Trend Test for Low-Coverage Next-Generation Sequence Data Controlling for Covariates
Low-coverage next-generation sequencing experiments assisted by statistical methods are popular in a genetic association study. Next-generation sequencing experiments produce genotype data that include allele read counts and read depths. For low sequencing depths, the genotypes tend to be highly unc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-02-01
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| Series: | Mathematics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-7390/8/2/217 |