Robust Linear Trend Test for Low-Coverage Next-Generation Sequence Data Controlling for Covariates
Low-coverage next-generation sequencing experiments assisted by statistical methods are popular in a genetic association study. Next-generation sequencing experiments produce genotype data that include allele read counts and read depths. For low sequencing depths, the genotypes tend to be highly unc...
Main Authors: | Jung Yeon Lee, Myeong-Kyu Kim, Wonkuk Kim |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-02-01
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Series: | Mathematics |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-7390/8/2/217 |
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