Design, synthesis, molecular docking study and biological evaluation of heteroaryl 2-phenoxypyridin-3-yl derivatives as lipoxygenase enzyme inhibitors

Introdution: Lipoxygenase enzyme is responsible for biosynthesis of leukotrienes that possess various pharmacological effects in the body. The beneficial therapeutic effects of lipoxygenase inhibitors have been proved in some diseases such as asthma, cancer and Alzheimer’s disease. So, the...

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Bibliographic Details
Main Authors: Zeinab Najjari, Zohreh Mirjalili, Hamid Nadri, Faezeh Rabbani, Alireza Moradi
Format: Article
Language:fas
Published: Shahid Sadoughi University of Medical Sciences 2018-10-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Subjects:
Online Access:http://jssu.ssu.ac.ir/browse.php?a_code=A-10-1617-1&slc_lang=en&sid=1