Circulating Extracellular Vesicles and Endothelial Damage in Sickle Cell Disease

Endothelial damage is central to the pathogenesis of many of the complications of sickle cell disease. Circulating extracellular vesicles (EVs) have been implicated in modulating endothelial behavior in a variety of different, diseases with vascular pathologies. As seen in other hemolytic diseases,...

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Bibliographic Details
Main Authors: Gabrielle Lapping-Carr, Joanna Gemel, Yifan Mao, Eric C. Beyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.01063/full