Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

The introduction of immune checkpoint blockade into the clinical practice resulted in improvement of survival of a significant portion of melanoma patients. Consequently, predictive biomarkers of response are needed to optimize patient's stratification and the development of combination therapi...

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Bibliographic Details
Main Authors: Cristina Maccalli, Diana Giannarelli, Carla Chiarucci, Ornella Cutaia, Gianluca Giacobini, Wouter Hendrickx, Giovanni Amato, Diego Annesi, Davide Bedognetti, Maresa Altomonte, Riccardo Danielli, Luana Calabrò, Anna Maria Di Giacomo, Francesco M. Marincola, Giorgio Parmiani, Michele Maio
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:OncoImmunology
Subjects:
cytotoxic t-lymphocyte antigen-4 (ctla-4)
metastatic melanoma
nkg2d ligands
programmed cell death-1 (pd-1)
t cell responses
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1323618

Internet

http://dx.doi.org/10.1080/2162402X.2017.1323618

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