Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury.

Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury.

Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. This study was undertaken to investigate the effects of wogonin, a flavonoid with potent anti-inflammatory properties, on functional and histological outcomes, brain edem...

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Bibliographic Details
Main Authors: Chien-Cheng Chen, Tai-Ho Hung, Yen-Ho Wang, Chii-Wann Lin, Pei-Yi Wang, Chun-Yen Lee, Szu-Fu Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260265?pdf=render

Internet

http://europepmc.org/articles/PMC3260265?pdf=render

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