Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

<p>Abstract</p> <p>Background</p> <p>Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the <it>tax </it>gene is thought to play a central role in oncogenesis. H...

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Bibliographic Details
Main Authors: Mueller Nancy, Maeda Michiyuki, Yasunaga Jun-ichirou, Nosaka Kisato, Taniguchi Yuko, Okayama Akihiko, Matsuoka Masao
Format: Article
Language:English
Published: BMC 2005-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/64