The Expression and Action of Decay-Accelerating Factor (CD55) in Human Malignancies and Cancer Therapy

Decay-accelerating factor (DAF, CD55) is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. Here DAF seems to exert different functions beyond its immunological role such as e.g. promotion of tumorigenesis, decrease of complement medi...

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Bibliographic Details
Main Authors: Jan-Henrik Mikesch, Kathrin Schier, Antje Roetger, Ronald Simon, Horst Buerger, Burkhard Brandt
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2006/814816