Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.

Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.

RNases are currently studied as non-mutagenic alternatives to the harmful DNA-damaging anticancer drugs commonly used in clinical practice. Many mammalian RNases are not potent toxins due to the strong inhibition by ribonuclease inhibitor (RI) presented in the cytoplasm of mammalian cells.In search...

Full description

Bibliographic Details
Main Authors: Evelina Edelweiss, Taras G Balandin, Julia L Ivanova, Gennady V Lutsenko, Olga G Leonova, Vladimir I Popenko, Alexander M Sapozhnikov, Sergey M Deyev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2413406?pdf=render

Internet

http://europepmc.org/articles/PMC2413406?pdf=render

Similar Items