Generation and functional characterization of MDSC-like cells

Generation and functional characterization of MDSC-like cells

Myeloid-derived suppressor cells (MDSC) are critical in regulating immune responses by suppressing antigen presenting cells (APC) and T cells. We previously observed that incubation of peripheral blood monocytes with interleukin (IL)-10 during their differentiation to monocyte-derived dendritic cell...

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Bibliographic Details
Main Authors: Annkristin Heine, Stefanie Andrea Erika Held, Jonas Schulte-Schrepping, Julia Friederike Andrea Wolff, Kathrin Klee, Thomas Ulas, Niklas Arndt Schmacke, Solveig Nora Daecke, Kati Riethausen, Joachim L. Schultze, Peter Brossart
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:OncoImmunology
Subjects:
apc
gitr
il-10
immunosuppression
mdsc
osteoactivin
pd-1
pd-l1
syndecan-4
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1295203

Internet

http://dx.doi.org/10.1080/2162402X.2017.1295203

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