Short-Course Rather Than Low-Dose Amphotericin B May Exert Potential Influence on Mortality in Cryptococcal Meningitis Patients Treated With Amphotericin B Plus Flucytosine Alone or in Combination With Fluconazole

Short-Course Rather Than Low-Dose Amphotericin B May Exert Potential Influence on Mortality in Cryptococcal Meningitis Patients Treated With Amphotericin B Plus Flucytosine Alone or in Combination With Fluconazole

BackgroundThe influence of Amphotericin B (AmB) dose and the addition of fluconazole (Flu) on the AmB + 5-flucytosine (5FC) regimen for cryptococcal meningitis (CM) treatment remain debatable.MethodsA retrospective study was conducted to compare 44 CM patients treated with AmB + 5FC and 78 CM patien...

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Bibliographic Details
Main Authors: Lijun Xu, Ran Tao, Jingjing Wu, Xiahong Dai, Caiqin Hu, Ying Huang, YaoKai Chen, Biao Zhu, Jianqin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
propensity score matching study
amphotericin
flucytosine
fluconazole
cryptococcal meningitis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02082/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02082/full

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