In-vitro inhibition of IFNγ<sup>+</sup> iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function

In-vitro inhibition of IFNγ<sup>+</sup> iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function

<p>Abstract</p> <p>Background</p> <p>IFNγ-producing CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> PBL represent a subtype of iTreg that are associated with good long-term graft outcome in renal transplant recipients and suppress al...

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Bibliographic Details
Main Authors: Daniel Volker, Sadeghi Mahmoud, Wang Haihao, Opelz Gerhard
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Immunology
Subjects:
IFNγ<sup>+</sup> iTreg
IFNγ<sup>+</sup>Foxp3<sup>+</sup>
IFNγ<sup>+</sup>CD127<sup>-</sup>
CD178
CD152
CD279
CD28
CD95
HLA-DR
Inhibition
Cell proliferation
Online Access:http://www.biomedcentral.com/1471-2172/13/47

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http://www.biomedcentral.com/1471-2172/13/47

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