A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.

Psychosocial stress is well known to be positively associated with subsequent depressive symptoms. Cortisol response to stress may be one of a number of biological mechanisms that links psychological stress to depressive symptoms, although the precise causal pathway remains unclear. Activity of the...

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Bibliographic Details
Main Authors: Beverly H Brummett, Michael A Babyak, Redford B Williams, Kathleen Mullan Harris, Rong Jiang, William E Kraus, Abanish Singh, Paul T Costa, Anastasia Georgiades, Ilene C Siegler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4267787?pdf=render