Down-regulated βIII-tubulin Expression Can Reverse Paclitaxel Resistance in A549/Taxol Cells Lines

Down-regulated βIII-tubulin Expression Can Reverse Paclitaxel Resistance in A549/Taxol Cells Lines

Background and objective Chemotherapy drug resistance is the primary causes of death in patients with pulmonary carcinoma which make tumor recurrence or metastasis. β-tubulin is the main cell targets of anti-microtubule drug. Increased expression of βIII-tubulin has been implicated in non-small cell...

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Bibliographic Details
Main Authors: Yinling ZHUO, Qisen GUO
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2014-08-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
A549/Taxol
RNA interference
βIII-tubulin
Taxol
 This work was supported by a grant from Medical and Health Project of Health Department of Shandong Province (to Qisen GUO)(No.2010GSF10258).
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2014.08.01

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2014.08.01

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