Enantiodivergent synthesis of tricyclic chromans: Remote nucleophilic groups switch selectivity in catalytic asymmetric cascade reactions of trifunctional substrates

An efficient and unified approach to the enantioselective synthesis of two important yet challenging classes of tricyclic chroman scaffolds by site-selective organocatalytic asymmetric cascade reactions of newly designed phenol-based trifunctional substrates bearing two reactive nucleophilic groups...

Full description

Bibliographic Details
Main Authors: Zhongwen Sun, Taochun Zha, Zhihui Shao
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2021-05-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554921000338