Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity

Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity

Lymphocyte migration is essential for the function of the adaptive immune system, and regulation of T cell entry into tissues is an effective therapy in autoimmune diseases. Little is known about the specific role of cytoskeletal effectors that mediate mechanical forces and morphological changes ess...

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Bibliographic Details
Main Authors: Scott B Thompson, Adam M Sandor, Victor Lui, Jeffrey W Chung, Monique M Waldman, Robert A Long, Miriam L Estin, Jennifer L Matsuda, Rachel S Friedman, Jordan Jacobelli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
cell migration
cytoskeleton
T cell
autoimmunity
FMNL1
actin
Online Access:https://elifesciences.org/articles/58046

Internet

https://elifesciences.org/articles/58046

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