Capping protein-controlled actin polymerization shapes lipid membranes

Cell membrane protrusions and invaginations are both driven by actin assembly but the mechanism leading to different membrane shapes is unknown. Using a minimal system and modelling the authors reconstitute the deformation modes and identify capping protein as a regulator of both deformation types.

Bibliographic Details
Main Authors: Katharina Dürre, Felix C. Keber, Philip Bleicher, Fridtjof Brauns, Christian J. Cyron, Jan Faix, Andreas R. Bausch
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03918-1