Rab25-Mediated EGFR Recycling Causes Tumor Acquired Radioresistance

Summary: Tumor acquired radioresistance remains as the major limit in cancer radiotherapy (RT). Rab25, a receptor recycling protein, has been reported to be enhanced in tumors with aggressive phenotype and chemotherapy resistance. In this study, elevated Rab25 expression was identified in an array o...

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Bibliographic Details
Main Authors: Lu Zhang, Bowen Xie, Yanfang Qiu, Di Jing, Jing Zhang, Yumei Duan, Zhi Li, Ming Fan, Jiang He, Yuanzheng Qiu, Rong Tan, Jian Jian Li, Lun-Quan Sun
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301814