Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis

Metastasis is a multi-step process in which direct crosstalk between cancer cells and their microenvironment plays a key role. Here, we assessed the effect of paired tumor-associated and normal lung tissue mesenchymal stem cells (MSCs) on the growth and dissemination of primary human lung carcinoma...

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Bibliographic Details
Main Authors: Giulia Fregni, Mathieu Quinodoz, Emely Möller, Joanna Vuille, Sabine Galland, Carlo Fusco, Patricia Martin, Igor Letovanec, Paolo Provero, Carlo Rivolta, Nicolo Riggi, Ivan Stamenkovic
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418300719