Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin.

Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin.

To analyse if platelet responsiveness to aspirin (ASA) may be associated with a different ability of platelets to generate nitric oxide (NO).Platelets were obtained from 50 patients with stable coronary ischemia and were divided into ASA-sensitive (n = 26) and ASA-resistant (n = 24) using a platelet...

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Main Authors: Javier Modrego, Luis Azcona, Naiara Martín-Palacios, José J Zamorano-León, Antonio Segura, Pablo Rodríguez, Reddy Guerra, Juan Tamargo, Carlos Macaya, Antonio J López-Farré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869699?pdf=render

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http://europepmc.org/articles/PMC3869699?pdf=render

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