The Pathogenesis and Therapies of Striated Muscle Laminopathies

The Pathogenesis and Therapies of Striated Muscle Laminopathies

Emery-Dreifuss muscular dystrophy (EDMD) is a genetic condition characterized by early contractures, skeletal muscle weakness, and cardiomyopathy. During the last 20 years, various genetic approaches led to the identification of causal genes of EDMD and related disorders, all encoding nuclear envelo...

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Bibliographic Details
Main Authors: Astrid Brull, Blanca Morales Rodriguez, Gisèle Bonne, Antoine Muchir, Anne T. Bertrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Physiology
Subjects:
Emery-Dreifuss muscular dystrophy (EDMD)
A-type lamins
nuclear envelope (NE)
muscular dystrophy (MD)
cardiomyopathy
emerin
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01533/full

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https://www.frontiersin.org/article/10.3389/fphys.2018.01533/full

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