Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae.
Correct repair of DNA double-strand breaks (DSBs) is critical for maintaining genome stability. Whereas gene conversion (GC)-mediated repair is mostly error-free, repair by break-induced replication (BIR) is associated with non-reciprocal translocations and loss of heterozygosity. We have previously...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4830573?pdf=render |