Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.

Cell-mediated immune responses are known to be critical for control of mycobacterial infections whereas the role of B cells and humoral immunity is unclear. B cells can modulate immune responses by secretion of immunoglobulin, production of cytokines and antigen-presentation. To define the impact of...

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Bibliographic Details
Main Authors: Egídio Torrado, Jeffrey J Fountain, Richard T Robinson, Cynthia A Martino, John E Pearl, Javier Rangel-Moreno, Michael Tighe, Robert Dunn, Andrea M Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3627912?pdf=render