Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury.

Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury.

Epigenetic predisposition is thought to critically contribute to adult-onset disorders, such as retinal neurodegeneration. The histone methyltransferase, enhancer of zeste homolog 2 (Ezh2), is transiently expressed in the perinatal retina, particularly enriched in retinal ganglion cells (RGCs). We p...

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Bibliographic Details
Main Authors: Lin Cheng, Lucy J Wong, Naihong Yan, Richard C Han, Honghua Yu, Chenying Guo, Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho, Dong Feng Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5800601?pdf=render

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http://europepmc.org/articles/PMC5800601?pdf=render

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