Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesiss⃞

Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesiss⃞

Ceramide kinase (CERK) is a critical mediator of eicosanoid synthesis, and its product, ceramide-1-phosphate (C1P), is required for the production of prostaglandins in response to several inflammatory agonists. In this study, mass spectrometry analysis disclosed that the main forms of C1P in cells w...

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Bibliographic Details
Main Authors: Nadia F. Lamour, Robert V. Stahelin, Dayanjan S. Wijesinghe, Michael Maceyka, Elaine Wang, Jeremy C. Allegood, Alfred H. Merrill, Jr., Wonhwa Cho, Charles E. Chalfant
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
ceramide-1-phosphate
prostaglandins
phospholipase A2
inflammation
arachidonic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752042557X

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http://www.sciencedirect.com/science/article/pii/S002222752042557X

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