Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice

Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice

Abstract Background Insulin replenishment is critical for patients with type 1 diabetes; however, current treatments such as pancreatic islet transplantation and insulin injection are not ideal. In addition to stem cell or gene therapy alone, stem cell combined with gene therapy may provide a new ro...

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Bibliographic Details
Main Authors: Qing Fang, Min Zhai, Shan Wu, Xiaogen Hu, Zhan Hua, Huizhuo Sun, Jing Guo, Wenjian Zhang, Zai Wang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Adipocyte-derived stem cell
Gene therapy
Adipogenic differentiation
Microcarrier
Diabetes
Online Access:http://link.springer.com/article/10.1186/s13287-019-1135-y

Internet

http://link.springer.com/article/10.1186/s13287-019-1135-y

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