Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters

Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters

Four lipophilicity descriptors (RM0, b, C0, PC1) for twelve coumarine derivatives were determined by reversed-phase thin-layer chromatography in order to analyze which descriptor best describes the lipophilicity of coumarines investigated. Moreover, possible chemical toxicity of coumarins, expre...

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Bibliographic Details
Main Authors: Rabtti El Hadi M.A., Natić Maja M., Milojković-Opsenica Dušanka M., Trifković Jelena Đ., Tosti Tomislav, Vučković Ivan M., Vajs Vlatka, Tešić Živoslav Lj.
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
lipophilicity parameters
thin-layer chromatography
toxicity
partial least squares regression
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200091R.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200091R.pdf

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