Immune tolerance induction using fetal directed placental injection in rodent models: a murine model.

Immune tolerance induction using fetal directed placental injection in rodent models: a murine model.

OBJECTIVES:Induction of the immune response is a major problem in replacement therapies for inherited protein deficiencies. Tolerance created in utero can facilitate postnatal treatment. In this study, we aimed to induce immune tolerance towards a foreign protein with early gestational cell transpla...

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Bibliographic Details
Main Authors: Kei Takahashi, Masayuki Endo, Takekazu Miyoshi, Mitsuhiro Tsuritani, Yukiko Shimazu, Hiroshi Hosoda, Kotaro Saga, Katsuto Tamai, Alan W Flake, Jun Yoshimatsu, Tadashi Kimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395343?pdf=render

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http://europepmc.org/articles/PMC4395343?pdf=render

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