Decreased HIV-specific T-regulatory responses are associated with effective DC-vaccine induced immunity.

Decreased HIV-specific T-regulatory responses are associated with effective DC-vaccine induced immunity.

The role of regulatory T cells (Tregs) in vaccination has been poorly investigated. We have reported that vaccination with ex vivo-generated dendritic-cells (DC) loaded with HIV-lipopeptides (LIPO-5-DC vaccine) in HIV-infected patients was well tolerated and highly immunogenic. These responses and t...

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Bibliographic Details
Main Authors: Vedran Brezar, Nicolas Ruffin, Laura Richert, Mathieu Surenaud, Christine Lacabaratz, Karolina Palucka, Rodolphe Thiébaut, Jacques Banchereau, Yves Levy, Nabila Seddiki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004752

Internet

https://doi.org/10.1371/journal.ppat.1004752

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