Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study.

<h4>Background</h4>There is significant heterogeneity in the clinical expression of structural brain abnormalities, including Alzheimer's disease biomarkers. Some individuals preserve their memory despite the presence of risk factors or pathological brain changes, indicating resilie...

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Main Authors: Anya Topiwala, Sana Suri, Charlotte Allan, Vyara Valkanova, Nicola Filippini, Claire E Sexton, Verena Heise, Enikő Zsoldos, Abda Mahmood, Archana Singh-Manoux, Clare E Mackay, Mika Kivimäki, Klaus P Ebmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211273